Ribosomal protein S6 kinase phospho-Ser418 RPS6KB1 Polyclonal Antibody

Specification:100 µg
Applications:Dot-Pep, ELISA
Immunogne:Rabbit polyclonal antibody raised against synthetic phosphopeptides of RPS6KB1.
Description:This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.
For research use only, not for diagnostic or therapeutic use.

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